I would say London because it is the only city from the original games that hasn't been done.
That and I think it has excellent potential for storyline. Same with Japan, but I don't think an asian version would relate well enough with the predominantly western audience this game markets to. I'd love to play it, but I don't think it would sell as well aned I think Rockstar likely feels the same way.
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And the currently popular Africa.
That would be an entirely different kind of game. Call it Grand Theft Country.
__________________ Fingerbang:
1.) The sexual act where a finger is inserted into the vagina or anus. Headbang:
1.) To vigorously nod your head up and down.